A gentle heating and cooling cream for relief of pain and discomfort from arthritis, neuralgia, shingles, joint pain and muscle strains and sprains. Adult dose: apply topically to affected area 3 times a day for at least a week. Apply with cotton bal (or wash hands well after use!) Avoid contact with eyes, face and mucous membranes. Do not use on infections, or broken or inflamed skin. Use as directed by a qualified health practitioner. May take up to two weeks for full effect . symptoms may seem temporarily aggravated, followed by pain reduction or elimination.